MOTS-C (Mitochondrial Open Reading Frame of the 12S rRNA Type-C) is a 16-amino acid peptide encoded within the mitochondrial genome, representing a member of the mitochondrial-derived peptide (MDP) family. Published research has established MOTS-C as a mitochondrial signaling molecule with documented effects on AMPK activation, folate-methionine cycle regulation, and cellular metabolic stress responses.
The discovery and characterization of MOTS-C in published literature has advanced understanding of mitochondrial retrograde signaling — the process by which mitochondrial-encoded factors influence nuclear gene expression. Researchers have documented its effects on glucose metabolism, skeletal muscle bioenergetics, and metabolic homeostasis pathways in cell-based and animal model systems.
Each 10mg vial contains lyophilized MOTS-C with verified sequence identity and purity. The preparation is manufactured under conditions optimized for this unique mitochondrial-derived peptide.
For laboratory research use only. Not intended for human or animal administration.
