Follistatin 344 is a recombinant form of the full-length human follistatin glycoprotein, comprising 344 amino acids including the signal peptide region. Published research has established follistatin’s role as a high-affinity binding protein for activin and other TGF-beta superfamily members, with particular attention to its neutralization of myostatin signaling documented in molecular endocrinology literature.
The compound has been utilized in published studies examining TGF-beta superfamily signaling dynamics, activin-mediated transcriptional programs, and Smad-dependent pathway regulation. Researchers have documented follistatin 344’s binding stoichiometry and kinetic parameters with multiple ligands using surface plasmon resonance, co-immunoprecipitation, and functional reporter assay systems.
Each 1mg vial contains recombinant follistatin 344 produced in mammalian expression systems and verified for biological activity, protein identity, and purity through SDS-PAGE, Western blot, and functional binding assays.
Exclusively for in-vitro and preclinical research. Not for human or animal administration.
